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KMID : 1007020110090010046
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Korean Soceity of Osteroporosis
2011 Volume.9 No. 1 p.46 ~ p.50
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Decreased Bone Mineral density of Spine in Patients with Invasive Cervical Cancer
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Choi Hoon
Jung Min-Hyung
Ji Yong-Il
Jung Hye-Ok
Lee Ji-Young
Choi Won-Jun
Kim A-Ri
Choi Jong-Soon
Oh Young-Rim
Kim Heung-Yeol
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Abstract
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Objectives: To investigate the spinal bone mineral density (BMD) in patients with invasive cervical cancer without bone metastases.
Methods: We measured spinal bone mineral densities by dual-photon absorptiometry in 119 patients with invasive uterine cervical cancer and compared them with measurements from 135 control women.
Results: When adjusted for age, mean bone mineral density in patients with uterine cervical cancer was 13.9% lower (P=0.0003) and age-matched percentiles were 9.2% lower (P=0.0003) than in control women. The deficits in bone mineral density and age-matched percentiles were confined to the uterine cervical cancer patients in their fifties.
Conclusions: Our study results suggest that patients with invasive cervical cancer have a lower spinal BMD, resulting in an increased risk of osteoporosis.
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KEYWORD
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Bone mineral density, Cervical cancer, Osteoporosis
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